Patent · US Expired

Receptor-based interaction trap

US7855270B2 · kind B2 · utility

3Cited by

15References

9Claims

0Family size

Assignee

VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW · BE

Inventors

Sven Eyckerman · Nazareth, BE
Xaveer van Ostade · Lokeren, BE
Joel Vandekerckhove · Loppem, BE
Annick Verhee · Lichtervelde, BE
Jan Tavernier · Balegem, BE

Key dates

Filing date	Nov 22, 2002
Grant date	Dec 21, 2010
Priority date	—
Expiry date	Oct 11, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2799/06
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention discloses a recombinant receptor comprising an extracellular ligand-binding domain and a cytoplasmic domain that comprises a heterologous bait polypeptide. The recombinant receptor is activated by binding of a ligand to the ligand binding domain and by binding of a prey polypeptide to the heterologous bait peptide. The present invention also discloses a method for detecting compound-compound binding using the recombinant receptor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.