Plant acyltransferases specific for long-chained, multiply unsaturated fatty acids

US7855321B2 · kind B2 · utility

Assignee

• The University of Bristol · GB

Inventors

• Andreas Renz · Schifferstadt, DE
• Jörg Bauer · Weingarten, DE
• Margit Frentzen · Aachen, DE
• Nursen Sözer · Übach-Palenberg, DE
• Stobart Keith · Bristol, GB
• Thomas Fraser · Newton, US
• Colin M. Lazarus · Bristol, GB
• Baoxiu Qi · Bath, GB
• Amine Abbadi · Plettenberg, DE
• Ernst Heinz · Hamburg, DE

Key dates

• Filing date: Mar 26, 2004
• Grant date: Dec 21, 2010
• Expiry date: Feb 22, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P7/6472
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which code for polypeptides with acyl transferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences which code for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids.The invention furthermore relates to the nucleic acid sequences, nucleic acid constructs, vectors and organisms comprising the nucleic acid sequences according to the invention, vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors.A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.