Pan cancer oncolytic vectors and methods of use thereof
US7858083B2 · kind B2 · utility
4Cited by
24References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 4, 2008 |
| Grant date | Dec 28, 2010 |
| Priority date | — |
| Expiry date | Dec 4, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Replication-competent adenoviral vectors which selectively replicate in cancer cells are provided. The replication-competent viral vectors comprise an E2F responsive promoter and/or a telomerase promoter operatively linked to an adenoviral coding region. The replication-competent adenoviral vectors effectively replicate in a variety of types of cancer cells and find broad utility in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.