Method of determining inhibition of binding to TRPM7 protein
US7858322B2 · kind B2 · utility
75Cited by
0References
6Claims
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Key dates
| Filing date | Dec 22, 2004 |
| Grant date | Dec 28, 2010 |
| Priority date | — |
| Expiry date | Dec 22, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to methods of reducing the damaging effect of an injury to mammalian cells by treatment with compounds which reduce cell death or dysfunction, including cellular damage following episodes of tissue ischemia, trauma, epilepsy, and acute or chronic degeneration. The invention discloses methods of treating these disorders by administering inhibitors that disrupt protein-protein interactions involved in these disorders, screening methods to identify such inhibitors and specific compositions useful for treating these disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.