Method for detecting binding events using micro-X-ray fluorescence spectrometry
US7858385B2 · kind B2 · utility
21Cited by
16References
16Claims
0Family size
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Key dates
| Filing date | May 16, 2001 |
| Grant date | Dec 28, 2010 |
| Priority date | — |
| Expiry date | May 16, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/19
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method for detecting binding events using micro-X-ray fluorescence spectrometry. Receptors are exposed to at least one potential binder and arrayed on a substrate support. Each member of the array is exposed to X-ray radiation. The magnitude of a detectable X-ray fluorescence signal for at least one element can be used to determine whether a binding event between a binder and a receptor has occurred, and can provide information related to the extent of binding between the binder and receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.