Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions
US7858608B2 · kind B2 · utility
13Cited by
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5Claims
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Key dates
| Filing date | May 4, 2009 |
| Grant date | Dec 28, 2010 |
| Priority date | — |
| Expiry date | May 4, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula (I)wherein:R1 is hydrogen or an alkyl group;R2 is hydrogen or a halogen, nitro, alkyloxy, amino or carboxy group;Y is CH2, oxygen or sulfur;n is an integer from 1 to 4, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof for the treatment of FXR-mediated diseases or conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.