Patent · US Active

Ligands for transition-metal-catalyzed cross-couplings, and methods of use thereof

US7858784B2 · kind B2 · utility

17Cited by

21References

42Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Stephen L. Buchwald · Newton, US
Brett P. Fors · Goleta, US
David S. Surry · Boston, US

Key dates

Filing date	Dec 12, 2008
Grant date	Dec 28, 2010
Priority date	—
Expiry date	Dec 12, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F15/006
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Ligands for transition metals are disclosed herein, which may be used in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The disclosed methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition-metal-catalyzed cross-coupling reactions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.