Process for producing 6-dimethylaminomethyl-phenyl-cyclohexane-1,3-diols

US7858826B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Wolfgang Hell · Aachen, DE
• Oswald Zimmer · Würselen, DE
• Markus Kegel · Aachen, DE
• Olaf Schaefer · Biberach an der Riß, DE
• Felix Spindler · Starrkirch-Wil, CH
• Anita Schnyder · Allschwil, CH
• Urs Siegrist · Eiken, CH
• Detlef Heller · Rostock, DE
• Hans-Joachim Drexler · Rostock, DE

Key dates

• Filing date: Feb 27, 2009
• Grant date: Dec 28, 2010
• Expiry date: Apr 21, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for producing 6-dimethylaminomethyl-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-1,3-diols from 6-dimethylaminomethyl-1-hydroxy-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-3-ones by catalytic hydrogenation in the presence of heterogeneous or homogeneous catalysts, or by using metal hydrides.