Patent · US Active

Dendrimers as molecular translocators

US7862807B2 · kind B2 · utility

10Cited by

9References

12Claims

0Family size

Assignee

University of California, San Diego · US

Inventors

Murray Goodman · Village of La Jolla, US
Churl Min Seong · San Diego, US
Guido Harms · Schifferstadt, DE

Key dates

Filing date	Jul 18, 2003
Grant date	Jan 4, 2011
Priority date	—
Expiry date	Jan 19, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G83/003
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Transport molecules include a dendrimer and a biologically active molecule. The dendrimer of such transport molecules includes at least one guanidine group, at least one protonated guanidine group, at least one protected guanidine group, at least one amidine group, at least one protonated amidine group, at least one protected amidine group, at least one ureido group, at least one protonated ureido group, at least one protected ureido group, at least one thioureido group, at least one protonated thioureido group, or at least one protected thioureido group. The biologically active molecule is bonded to the dendrimer. A method of increasing the bioavailability of a drug includes bonding the drug to a dendrimer of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.