Patent · US Active

Heterocycle derivatives as histone deacetylase (HDAC) inhibitors

US7863294B2 · kind B2 · utility

2Cited by

0References

18Claims

0Family size

Assignee

Istituto di Recerche di Biologia Molecolare P. Angeletti S.R.L. · IT

Inventors

Barbara Attenni · Roma, IT
Federica Ferrigno · Pomezia, IT
Philip Jones · Houston, US
Raffaele Ingenito · Pomezia, IT
Olaf Kinzel · Heidelberg, DE
Laura Llauger Bufi · Pomezia, IT
Jesus Maria Ontoria · Barcelona, ES
Giovanna Pescatore · Cosenza, IT
Michael Rowley · Roma, IT
Rita Scarpelli · Pomezia, IT
Carsten Schultz · Heidelberg, DE

Key dates

Filing date	Dec 9, 2005
Grant date	Jan 4, 2011
Priority date	—
Expiry date	Oct 10, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula I:or pharmaceutically acceptable salts or tautomers thereof, which are inhibitors of histone deacetylase (HDAC). The compounds of the present invention are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.