Method and apparatus for digital differential ion mobility separation
US7863562B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 22, 2007 |
| Grant date | Jan 4, 2011 |
| Priority date | — |
| Expiry date | Apr 24, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/624
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for differential mobility separation of ions using digital-drive based high voltage fast switching electronics. The digital waveform delivered to the spectrometer is characterized by at least two substantially rectangular pulses of different amplitude and polarity. The control circuitry allows for waveform frequency, duty cycle and pulse amplitudes to be varied independently. Balanced as well as unbalanced asymmetric waveforms can be designed for optimum differential mobility separation of ions. The digital drive is designed for differential mobility spectrometers including parallel plate and segmented plate multipoles of planar symmetry, as well as multipoles of cylindrical symmetry, which may optionally be arranged in series. The use of the digital drive establishes alternating electric fields during which the displacement as a result of ion oscillation is determined by mobility coefficients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.