Immunoglobulin fusion proteins

US7867491B2 · kind B2 · utility

Assignees

• GENEXINE, INC. · KR
• POSTECH ACADEMY-INDUSTRY FOUNDATION POHANG UNIVERSITY OF SCIENCE AND TECHNOLOGY · KR

Inventors

• Sehwan Yang · Dongmyeong-myeon, KR
• Young Chul Sung · Seoul, KR

Key dates

• Filing date: May 30, 2008
• Grant date: Jan 11, 2011
• Expiry date: May 30, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are fusion proteins comprising a biologically active molecule and an immunoglobulin (Ig) Fc domain which is linked to the biologically active molecule. The Fc domain is a hybrid human Fc domain of (i) IgG1, IgG2 or IgG4 or (ii) IgG4 and IgD. The hybrid Fc is useful as a carrier of biologically active molecules.