HX2004-6 polypeptide expressed in cancerous cells

US7867731B2 · kind B2 · utility

Assignee

• Novartis Vaccines and Diagnostics, Inc. · US

Inventors

• Christoph Reinhard · Alameda, US
• Anne Jefferson · University City, US
• Vivien Chan · Emeryville, US
• Joerg Kaufmann · Isenbüttel, DE
• Hong Xin · Bonsall, US
• Giulia C. Kennedy · San Francisco, US
• Greg Harrowe · Emeryville, US
• Hamiduddin Khoja · Emeryville, US
• Venkatakrishna Shyamala · Oakland, US

Key dates

• Filing date: Oct 28, 2004
• Grant date: Jan 11, 2011
• Expiry date: May 10, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention provides polynucleotides, as well as polypeptides encoded thereby, that are differentially expressed in cancer cells. These polynucleotides are useful in a variety of diagnostic and therapeutic methods. The present invention further provides methods of reducing growth of cancer cells. These methods are useful for treating cancer.