Fusion protein of exendin-4 to a transferrin (Tf) polypeptide
US7867972B2 · kind B2 · utility
19Cited by
45References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 2007 |
| Grant date | Jan 11, 2011 |
| Priority date | — |
| Expiry date | Feb 27, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/03
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides fusion proteins comprising an exendin-4 fused to a transferrin (Tf) via a polypeptide linker, as well as corresponding nucleic acid molecules, vectors, host cells, and pharmaceutical compositions. The invention also provides the use of the exendin-4/Tf fusion proteins for treatment of Type II diabetes, obesity, and to reduce body weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.