Compounds and compositions as protein kinase inhibitors
US7868018B2 · kind B2 · utility
7Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 9, 2006 |
| Grant date | Jan 11, 2011 |
| Priority date | — |
| Expiry date | Aug 9, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds of Formula I:wherein R1-R6 are described in the Summary of the Invention; the pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, BMX, BTK, CHK2, b-RAF, c-RAF, CSK, c-SRC, Fes, FGFR3, Flt3, IKKα, IKKβ, JNK2α2, Lck, Met, MKK4, MKK6, MST2, NEK2, p70S6K, PDGFRβ, PKA, PKBα, PKD2, Rsk1, SAPK2α, SAPK2β, SAPK3, SGK, Tie2 and TrkB kinases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.