Methods and systems to identify operational reaction pathways

US7869957B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Bernhard O. Palsson · Village of La Jolla, US
• Markus W. Covert · San Diego, US
• Markus Herrgard · San Diego, US

Key dates

• Filing date: Apr 27, 2004
• Grant date: Jan 11, 2011
• Expiry date: Dec 6, 2024

Classification

• Technology area (CPC G): Physics
• CPC primary: G16B40/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention provides a method of refining a biosystem reaction network. The method consists of: (a) providing a mathematical representation of a biosystem; (b) reconciling said mathematical representation of said biosystem; (c) determining differences between observed behavior of a biosystem and in silico behavior of said mathematical representation of said biosystem under similar conditions; (d) modifying a structure of said mathematical representation of said biosystem, and (e) determining differences between said observed behavior of said biosystem and in silico behavior of said modified mathematical representation of said biosystem under similar conditions.