Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity

US7871998B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Susanne Alenfalk · Mölndal, SE
• Mikael Dahlstrom · Timrå, SE
• Fana Hunegnaw · Mölndal, SE
• Staffan Po Karlsson · Mölndal, SE
• Malin Lemurell · Mölndal, SE
• Ann-Margret Lindqvist · Timrå, SE
• Tore Skjaret · Hultsfred, SE
• Ingemar Starke · Gothenburg, SE

Key dates

• Filing date: Dec 21, 2004
• Grant date: Jan 18, 2011
• Expiry date: Oct 2, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.