Optically active isomers of ketotifen and therapeutically active metabolites thereof
US7872025B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Feb 12, 2009 |
| Grant date | Jan 18, 2011 |
| Priority date | — |
| Expiry date | Feb 12, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Racemic norketotifen, racemic 10-hydroxy-ketotifen, racemic 10-hydroxy-nor-ketotifen and optically active isomers of ketotifen, norketotifen, 10-hydroxy-ketotifen and 10-hydroxy-norketotifen were found to have antiallergic and anti-inflammatory effects while being devoid of the severe dose-limiting sedative side effects of Ketotifen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.