3-aminoindazoles

US7872039B2 · kind B2 · utility

Assignee

• Merck Patentgesellschaft · DE

Inventors

• Dieter Dorsch · Ober-Ramstadt, DE
• Lars Burgdorf · Frankfurt am Main, DE
• Rolf Gericke · Seeheim-Jugenheim, DE
• Norbert Beier · Reinheim, DE
• Werner Mederski · Zwingenberg, DE
• Florian Lang · Gilching, DE

Key dates

• Filing date: Apr 4, 2005
• Grant date: Jan 18, 2011
• Expiry date: Apr 19, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel 3-aminoindazoles of the formula (I) are SGK inhibitors and can be used for the treatment of SGK-induced diseases and conditions, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in fibrosis and inflammatory processes of any type.