Process for producing biphosphonic acids and forms thereof

US7872144B2 · kind B2 · utility

Assignee

• Jubilant Organosys Limited · IN

Inventors

• Satish Chandra Pandey · Noida, IN
• Hussain Haider · Noida, IN
• Sudhanshu Saxena · Sidhauli, IN
• Manoj Kumar Singh · Sayla, IN
• Rajesh Kumar Thaper · Jammu, IN
• Sushil Kumar Dubey · Noida, IN

Key dates

• Filing date: Jun 13, 2005
• Grant date: Jan 18, 2011
• Expiry date: Oct 28, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6561
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed herein is a process for producing bisphosphonic acids and salts thereof. The process comprising reacting a carboxylic acid of Formula [I] with phosphorous acid and halophosphorus compound in the presence of a solvent selected from aliphatic hydrocarbon or water miscible cyclic ether. Further, the present invention also provides novel forms of bisphosphonic acids and process for preparation thereof.