Biointerface membranes incorporating bioactive agents
US7875293B2 · kind B2 · utility
178Cited by
354References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 10, 2004 |
| Grant date | Jan 25, 2011 |
| Priority date | — |
| Expiry date | May 29, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48707
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.