Patent · US Active

Method and device for sample preparation

US7875462B2 · kind B2 · utility

3Cited by

1References

16Claims

0Family size

Assignee

PHYNEXUS, INC. · US

Inventors

Douglas T. Gjerde · Saratoga, US
Allen Burge · Sunnyvale, US
Ronald Jones · Mountain View, US
Mark Abel · San Jose, US

Key dates

Filing date	Mar 23, 2010
Grant date	Jan 25, 2011
Priority date	—
Expiry date	Mar 23, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/255
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column, often between two frits. In some embodiments, the extraction columns employ modified pipette tips as column bodies. In some embodiments, the extraction columns are comprised of frits having a low pore. In some embodiments, the frits of the extraction columns have a pore volume of less than one microliter or less than 10% of the interstitial volume of the bed of extraction media.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.