Cyclohepta[b]pyridine-3-carbonylguanidine derivative and pharmaceutical product containing same
US7875625B2 · kind B2 · utility
1Cited by
4References
6Claims
0Family size
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Key dates
| Filing date | Feb 16, 2006 |
| Grant date | Jan 25, 2011 |
| Priority date | — |
| Expiry date | Aug 9, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na+/H+ exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1):wherein R1 is a group selected from a sulfo group, a sulfoxy group, —OCONH—(CH2CH2O)n—SO3H and the following formulas:R2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10,
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.