Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof
US7875627B2 · kind B2 · utility
4Cited by
3References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2005 |
| Grant date | Jan 25, 2011 |
| Priority date | — |
| Expiry date | Nov 27, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses fused thienopyridyl compounds of general formula (I)wherein X1-X6, R5-R7, Z1 and L are as defined in the description. The resent invention also discloses a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain, urinary incontinence, bladder overactivity, and inflammatory thermal hyperalgesia in mammals, and pharmaceutical compositions including those compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.