Patent · US Active

Process for making asenapine

US7875729B2 · kind B2 · utility

7Cited by

1References

22Claims

0Family size

Assignee

Synthon B.V. · NL

Inventors

Jie Zhu · San Jose, US
Rolf Keltjens · Nijmegen, NL
Judith Firet · Ede, NL

Key dates

Filing date	Dec 21, 2007
Grant date	Jan 25, 2011
Priority date	—
Expiry date	Feb 18, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/044
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Asenapine and related trans-isomer bicyclic compounds can be obtained by reducing a compound of formula (C) to preferentially form a trans-isomer compound of formula (D), followed by subsequent ring closure to form a compound of formula (B) such as asenapine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.