Patent · US Active

Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)Carbonyl]-1H-pyrrole-1-heptanoic acid

US7875731B2 · kind B2 · utility

7Cited by
3References
4Claims
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Key dates

Filing dateApr 25, 2005
Grant dateJan 25, 2011
Priority date
Expiry dateDec 24, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/037
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease.

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