Monodisperse mesoporous silica microspheres formed by evaporation-induced self-assembly of surfactant templates in aerosoles
US7879304B1 · kind B1 · utility
1Cited by
7References
23Claims
0Family size
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Key dates
| Filing date | Jan 16, 2008 |
| Grant date | Feb 1, 2011 |
| Priority date | — |
| Expiry date | Mar 14, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1617
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides for evaporation induced self-assembly (EISA) within microdroplets produced by a vibrating orifice aerosol generator (VOAG) for the production of monodisperse mesoporous silica particles. The process of the present invention exploits the concentration of evaporating droplets to induce the organization of various amphiphilic molecules, effectively partitioning a silica precursor to the hydrophilic regions of the structure. Promotion of silica condensation, followed by removal of the surfactant, provides ordered spherical mesoporous particles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.