Fabrication of a high resolution biological molecule detection device
US7879534B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 19, 2002 |
| Grant date | Feb 1, 2011 |
| Priority date | — |
| Expiry date | May 5, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5438
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method of manufacturing a detection device which involves providing a substrate having a layer of electrically conductive material and a first layer of photosensitive material. Next, the substrate is subjected to a first level photolithography treatment to produce an electrical conductor containing conductive fingers with spaces between them. Finally, biological probes are attached to the conductive fingers under conditions effective to form a gap between the biological probes on the spaced apart conductive fingers, whereby a target molecule, if present in a sample, can bind to a pair of the biological probes on the spaced apart conductive fingers to bridge the gap between the biological probes, allowing detection of the target molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.