Method of detecting mutations associated with thrombosis
US7879543B2 · kind B2 · utility
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2References
11Claims
0Family size
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Key dates
| Filing date | Nov 17, 2004 |
| Grant date | Feb 1, 2011 |
| Priority date | — |
| Expiry date | May 2, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method for the simultaneous identification of two or more single base changes in a plurality of target nucleotide sequences that are markers associated with cardiovascular diseases such as deep vein thrombosis and the like. Multiplex detection is accomplished using multiplexed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.