Patent · US Active

Crystalline antifungal compounds

US7879867B2 · kind B2 · utility

6Cited by

2References

16Claims

0Family size

Assignees

Palau Pharma, S.A. · ES
STIEFEL LABORATORIES, INC. · US

Inventors

Antonio Paredes · Tona, ES
Javier Bartroli Orpi · Barcelona, ES
Elies Molins Grau · Bellaterra, ES
Anna Roig Serra · Bellaterra, ES
Kevin G. Meyer · Zionsville, US
Keith Lorimer · West Lafayette, US

Key dates

Filing date	Aug 6, 2007
Grant date	Feb 1, 2011
Priority date	—
Expiry date	Sep 23, 2027

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P33/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2 -(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin -4(3H)-one, represented by formula II:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.