Patent · US Active

Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme

US7880001B2 · kind B2 · utility

5Cited by
14References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 29, 2005
Grant dateFeb 1, 2011
Priority date
Expiry dateJan 28, 2028

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/056
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.