Method for designing surfaces
US7881871B2 · kind B2 · utility
2Cited by
40References
22Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 10, 2004 |
| Grant date | Feb 1, 2011 |
| Priority date | — |
| Expiry date | May 3, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B20/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of producing a binding surface for a target molecule having a functional binding site, which method comprises: (i) identifying within the target molecule an anchor site which is remote from the functional binding site; (ii) generating a pharmacophore model for the anchor site; (iii) using the pharmacophore model to identify an anchor site binding ligand; and (iv) providing the anchor site binding ligand on a surface of a substrate such that the ability of the anchor site binding ligand to bind to the anchor site is preserved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.