Antigen constructs useful in the detection and differentiation of antibodies to HIV
US7883845B2 · kind B2 · utility
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14References
7Claims
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Key dates
| Filing date | Oct 6, 2009 |
| Grant date | Feb 8, 2011 |
| Priority date | — |
| Expiry date | Oct 6, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/162
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.