Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
US7884179B2 · kind B2 · utility
16Cited by
8References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 12, 2006 |
| Grant date | Feb 8, 2011 |
| Priority date | — |
| Expiry date | Mar 29, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel gene 08P1D4 (also designated STEAP-1) and its encoded protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.