Method for in vitro production of three-dimensional vital cartilage tissue and use thereof as transplant material

US7887843B2 · kind B2 · utility

Assignee

• CO.DON AG · DE

Inventors

• Jeanette Libera · Berlin, DE
• Ursula Anderer · Berlin, DE
• Karl-Gerd Fritsch · Berlin, DE
• Olivera Josimovic-Alasevic · Berlin, DE

Key dates

• Filing date: Mar 9, 2001
• Grant date: Feb 15, 2011
• Expiry date: Aug 13, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K35/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a remarkably simple method for the in vitro production of three-dimensional, vital and mechanically stable cartilage or bone tissue and to the use thereof as a transplantation material for treating cartilage or bone defects and degenerative diseases such as rheumatism or arthrosis, and to the use thereof in testing active substances and physical factors. The invention is also directed to the cartilage or bone tissue and therapeutical formulations produced thereby, e.g. injection solutions comprising such tissue.