Detection of methicillin-resistant and methicillin-sensitive Staphylococcus aureus in biological samples
US7888075B2 · kind B2 · utility
5Cited by
11References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2008 |
| Grant date | Feb 15, 2011 |
| Priority date | — |
| Expiry date | Dec 7, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods of identifying a methicillin-resistant Staphylococcus aureus (MRSA) or methicillin-sensitive Staphylococcus aureus (MSSA) in a sample. The present invention provides a diagnostic method comprising modification of sequences of S. aureus by converting non-methylated cytosine residues ultimately into thymidine residues in the target nucleic acid. The invention further provides for the detection of modified sequences derived from the spa gene, the mecA gene, and the integrated SCCmec cassette of S. aureus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.