Process for the preparation of dihydroxy esters and derivatives thereof
US7888083B2 · kind B2 · utility
3Cited by
28References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 27, 2010 |
| Grant date | Feb 15, 2011 |
| Priority date | — |
| Expiry date | Apr 27, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is provided for the preparation of a compound of formula (1)wherein R and R′ represent optionally substituted hydrocarbyl groups and X represents a hydrocarbyl linking group. The process comprises either the stereoselective reduction of the keto group in a dihydroxy keto precursor followed by selective esterification of a primary hydroxy, or selective esterification of a primary hydroxy of a dihydroxy keto precursor followed by stereoselective reduction of the keto group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.