Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
US7888092B2 · kind B2 · utility
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Key dates
| Filing date | Oct 30, 2009 |
| Grant date | Feb 15, 2011 |
| Priority date | — |
| Expiry date | Oct 30, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein is are polypeptides that include the protease domain of a type II transmembrane serine protease (MTSP) as a single chain. Methods using the polypeptides to identify compounds that modulate the protease activity of an MTSP are provided. Also provided are MTSPs designated MTSP3 and MTSP4 and a form of an MTSP designated MTSP6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.