Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit
US7888133B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 2002 |
| Grant date | Feb 15, 2011 |
| Priority date | — |
| Expiry date | Nov 3, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/806
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to method of detecting autoantibodies from patients suffering from rheumatoid arthritis. To this end, according to the invention, at least two peptide units are used of which at least one peptide unit comprises a part not derived from (pro)filaggrin, fibrin, fibrinogen, vimentin, cytokeratin 1 and cytokeratin 9, and which peptide unit comprises the motif XG, and a peptide unit comprising the motif XnonG, wherein X is a citrulline or an analogue thereof, and nonG is an amino acid other than glycine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.