Patent · US Active

Mitoquinone derivatives used as mitochondrially targeted antioxidants

US7888335B2 · kind B2 · utility

3Cited by
9References
52Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 23, 2004
Grant dateFeb 15, 2011
Priority date—
Expiry dateJun 27, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention relates to pharmaceutically acceptable amphiphilic antioxidant compounds, compositions and dosage forms comprising said compounds, and methods and uses reliant on said compounds. The exemplified compounds are all mitoquinone derivatives, being methoxyphenyl alkyl triphenylphosphonium or methoxy dioxocyclohexadiene alkyl triphenylphosphonium derivatives. The compounds, compositions, dosage forms, uses and methods are useful in, for example, the treatment of diseases or conditions associated with oxidative stress.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.