Patent · US Active

Compositions and methods for inhibiting growth and metastasis of melanoma

US7888355B2 · kind B2 · utility

0Cited by

0References

5Claims

0Family size

Assignee

Burnham Institute for Medical Research · US

Inventors

Ze′ev A. Ronai · San Diego, US
Anindita Bhoumik · San Diego, US
Nicholas D. P. Cosford · San Diego, US
Russell Dahl · Saint John, US

Key dates

Filing date	Aug 11, 2010
Grant date	Feb 15, 2011
Priority date	—
Expiry date	Aug 11, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/52
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provided derivatives of celastrol and compositions comprising acetyl isogambogic acid, celastrol, or a derivative thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.