HDM2 polypeptides

US7888474B2 · kind B2 · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Thomas Hesson · Cambridge, US
• Hung V. Le · Rockaway, US
• Yao-Dong Ma · Richardson, US
• Vincent S. Madison · Mountain Lakes, US
• Anthony F. Mannarino · Melrose, US
• Paul Reichert · Montville, US
• Gerald W. Shipps, Jr. · Stoneham, US
• Corey Strickland · Bound Brook, US
• Shahriar Shane Taremi · Cambridge, US
• Yaolin Wang · Short Hills, US
• Rumin Zhang · Edison, US
• Jose S. Duca · Cranford, US

Key dates

• Filing date: Mar 12, 2010
• Grant date: Feb 15, 2011
• Expiry date: Mar 12, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2299/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to HDM2 polypeptides and mutants thereof which are complexed with various compounds, e.g., HDM2 inhibitors.