Chiral 1,8-diarylnaphthalenes, methods of making them, and their use as sensors
US7888509B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 1, 2004 |
| Grant date | Feb 15, 2011 |
| Priority date | — |
| Expiry date | Jun 12, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
One aspect of the invention relates to 1,8-diarylnaphthalene compounds. In certain embodiments, a compound of the invention is an N-oxide of a 1,8-diarylnaphthalene. In certain embodiments, the aryl group is an optionally substituted acridyl group. In certain embodiments, a compound of the invention is a single steroisomer. In certain embodiments, a compound of the invention is a single enantiomer. Another aspect of the present invention relates to a method of detecting the presence of an analyte in a sample by monitoring the fluorescence of a compound of the invention in a sample. In certain embodiments, the analyte is a metal ion. Another aspect of the present invention relates to a method of determining the enantiomeric purity of an analyte by monitoring the fluorescence of a compound of the invention in the presence of the analyte. In certain embodiments, the analyte is a compound that is capable of hydrogen bonding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.