Patent · US Expired

Method of screening for gamma-secretase activity

US7892778B2 · kind B2 · utility

0Cited by

0References

11Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Edmund Hoppe · Krailling, DE
Gisela Peraus · Birkenfeld, DE
Jonathan Rothblatt · Bound Brook Junction, US
Ekkehard Leberer · Germering, DE
Luc Mercken · Châteauroux, FR
Sylvie Dreisler · Gros-Morne, FR

Key dates

Filing date	May 19, 2004
Grant date	Feb 22, 2011
Priority date	—
Expiry date	Jun 10, 2024

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/81
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to an improved process for determining γ-secretase activity and for detecting γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. In particular, the present invention relates to processes for the identification of a γ-secretase or of a cDNA which codes for a γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. Another embodiment of the present invention relates to processes for the identification of substances which can inhibit the activity of γ-secretase, or a γ-secretase-like proteinase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.