Screening process for antibacterial agents
US7892782B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 23, 2008 |
| Grant date | Feb 22, 2011 |
| Priority date | — |
| Expiry date | Apr 27, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method of preparing a phenotypically antibiotic-resistant subpopulation of stationary phase bacteria by treating stationary phase bacteria with high doses of antibacterial agents, the subpopulation thus identified, a process for identifying new antibacterial agents by testing against the antibiotic-resistant subpopulation, the compounds thus identified and their uses, particularly in treating bacterial infections involving dormant bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.