Recombinant vector containing infectious, viral genome sequences greater than 100 kb, method for producing same and use for the mutagenesis of the viral sequences

US7892822B1 · kind B1 · utility

Inventors

• Ulrich Koszinowski · Dießen am Ammersee, DE
• Martin Messerle · Hannover, DE
• Wolfram Brune · Bocholt, DE
• Gabriele Hahn · Bocholt, DE

Key dates

• Filing date: Jul 31, 1998
• Grant date: Feb 22, 2011
• Expiry date: Jul 31, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2800/204
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Recombinant vectors containing infectious viral genomic sequences as well as sequences of a cloning vehicle, a cell comprising the vector, a method for producing the vectors, a method of mutagenizing an infectious viral genomic sequence in the vector, and a vector obtained by the method.