Differentiation of cardiac and pulmonary causes of acute shortness of breath
US7892844B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 2007 |
| Grant date | Feb 22, 2011 |
| Priority date | — |
| Expiry date | Jun 19, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/32
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method for differentiating in a subject suffering from acute shortness of breath (dyspnea) between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes comprising the steps of determining the amount of pulmonary surfactant protein B (SP-B) in a sample of a subject, determining the amount of N-terminal pro-brain natriuretic peptide (NT-proBNP) in a sample of the subject, and differentiating between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes by comparing the determined amounts with reference amounts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.