2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions

US7893048B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Susanne Alenfalk · Mölndal, SE
• Mikael Dahlstrom · Timrå, SE
• Fana Hunegnaw · Mölndal, SE
• Staffan Po Karlsson · Mölndal, SE
• Malin Lemurell · Mölndal, SE
• Ingemar Starke · Gothenburg, SE

Key dates

• Filing date: Jun 21, 2006
• Grant date: Feb 22, 2011
• Expiry date: Nov 10, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K5/06026
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.