Pyridol[2,3-B]pyrazinones for use as stearoyl CoA desaturase inhibitors
US7893066B2 · kind B2 · utility
4Cited by
6References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 2008 |
| Grant date | Feb 22, 2011 |
| Priority date | — |
| Expiry date | May 18, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses pyrido[2,3-B]pyrazinones having the structure of Formula Ifor use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, oily skin conditions, metabolic syndrome, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.