Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic
US7893071B2 · kind B2 · utility
1Cited by
20References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 22, 2002 |
| Grant date | Feb 22, 2011 |
| Priority date | — |
| Expiry date | Jun 7, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to novel thalidomide derivative compounds that have activity as anti-angiogenic compounds. More particularly the compounds have the general structure: where R1 is selected from the group consisting of H, halo, alkyl, haloalkyl, —NH2, hydroxy and alkoxy; R2 is selected from the group consisting of optionally substituted bicyclic, optionally substituted aryl, and R6 is H, or C1-C8 alkyl; R19 is optionally substituted aryl; and m is 0-6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.